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In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli
BACKGROUND: Cyclodipeptide oxidases (CDOs) are enzymes involved in the biosynthesis of 2,5-diketopiperazines, a class of naturally occurring compounds with a large range of pharmaceutical activities. CDOs belong to cyclodipeptide synthase (CDPS)-dependent pathways, in which they play an early role i...
Autores principales: | Le Chevalier, Fabien, Correia, Isabelle, Matheron, Lucrèce, Babin, Morgan, Moutiez, Mireille, Canu, Nicolas, Gondry, Muriel, Lequin, Olivier, Belin, Pascal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487605/ https://www.ncbi.nlm.nih.gov/pubmed/32894164 http://dx.doi.org/10.1186/s12934-020-01432-y |
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