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hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β(1)/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats

OBJECTIVE: The basic pathological changes of primary ovarian insufficiency (POI) include ovarian tissue fibrosis and follicular development disorders. The human umbilical cord mesenchymal stem cell (hUMSC) transplantation has been shown an effective method to improve the ovarian function in POI rat...

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Detalles Bibliográficos
Autores principales:	Cui, Linlu, Bao, Hongchu, Liu, Zhongfeng, Man, Xuejing, Liu, Hongyuan, Hou, Yun, Luo, Qianqian, Wang, Siyuan, Fu, Qiang, Zhang, Hongqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487655/ https://www.ncbi.nlm.nih.gov/pubmed/32894203 http://dx.doi.org/10.1186/s13287-020-01904-3

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