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Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression
BACKGROUND: Colorectal cancer (CRC) development is generally accepted as a sequential process, with genetic mutations determining phenotypic tumor progression. However, matching genetic profiles with histological transition requires the analyses of temporal samples from the same patient at key stage...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487684/ https://www.ncbi.nlm.nih.gov/pubmed/32895052 http://dx.doi.org/10.1186/s12915-020-00844-x |