Isogenic models of hypertrophic cardiomyopathy unveil differential phenotypes and mechanism-driven therapeutics

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a prevalent and complex cardiovascular condition. Despite being strongly associated with genetic alterations, wide variation of disease penetrance, expressivity and hallmarks of progression complicate treatment. We aimed to characterize different huma...

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Detalles Bibliográficos
Autores principales: Bhagwan, Jamie R., Mosqueira, Diogo, Chairez-Cantu, Karolina, Mannhardt, Ingra, Bodbin, Sara E., Bakar, Mine, Smith, James G.W., Denning, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487780/
https://www.ncbi.nlm.nih.gov/pubmed/32531470
http://dx.doi.org/10.1016/j.yjmcc.2020.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487780/
https://www.ncbi.nlm.nih.gov/pubmed/32531470
http://dx.doi.org/10.1016/j.yjmcc.2020.06.003

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