Palmitoleic acid reduces high fat diet-induced liver inflammation by promoting PPAR-γ-independent M2a polarization of myeloid cells

Palmitoleic acid (POA, 16:1n-7) is a lipokine that has potential nutraceutical use to treat non-alcoholic fatty liver disease. We tested the effects of POA supplementation (daily oral gavage, 300 mg/Kg, 15 days) on murine liver inflammation induced by a high fat diet (HFD, 59% fat, 12 weeks). In HFD...

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Detalles Bibliográficos
Autores principales: Souza, Camila O., Teixeira, Alexandre A.S., Biondo, Luana Amorim, Silveira, Loreana Sanches, de Souza Breda, Cristiane N., Braga, Tarcio T., Camara, Niels O.S., Belchior, Thiago, Festuccia, William T., Diniz, Tiego A., Ferreira, Glaucio Monteiro, Hirata, Mario Hiroyuki, Chaves-Filho, Adriano B., Yoshinaga, Marcos Y., Miyamoto, Sayuri, Calder, Philip C., Sethi, Jaswinder K., Rosa Neto, José C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487782/
https://www.ncbi.nlm.nih.gov/pubmed/32738301
http://dx.doi.org/10.1016/j.bbalip.2020.158776

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