GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells

During early development, extrinsic triggers prompt pluripotent cells to begin the process of differentiation. When and how human embryonic stem cells (hESCs) irreversibly commit to differentiation is a fundamental yet unanswered question. By combining single-cell imaging, genomic approaches, and ma...

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Detalles Bibliográficos
Autores principales: Gunne-Braden, Alexandra, Sullivan, Adrienne, Gharibi, Borzo, Sheriff, Rahuman S.M., Maity, Alok, Wang, Yi-Fang, Edwards, Amelia, Jiang, Ming, Howell, Michael, Goldstone, Robert, Wollman, Roy, East, Philip, Santos, Silvia D.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487786/
https://www.ncbi.nlm.nih.gov/pubmed/32302522
http://dx.doi.org/10.1016/j.stem.2020.03.005

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