Efficient and rapid conversion of human astrocytes and ALS mouse model spinal cord astrocytes into motor neuron-like cells by defined small molecules

BACKGROUND: Motor neuron degeneration or loss in the spinal cord is the characteristic phenotype of motor neuron diseases or spinal cord injuries. Being proliferative and located near neurons, astrocytes are considered ideal cell sources for regenerating neurons. METHODS: We selected and tested diff...

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Detalles Bibliográficos
Autores principales: Zhao, An-Dong, Qin, Hua, Sun, Meng-Li, Ma, Kui, Fu, Xiao-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487818/
https://www.ncbi.nlm.nih.gov/pubmed/32892745
http://dx.doi.org/10.1186/s40779-020-00271-7

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