Topically applicated curcumin/gelatin-blended nanofibrous mat inhibits pancreatic adenocarcinoma by increasing ROS production and endoplasmic reticulum stress mediated apoptosis

BACKGROUND: Pancreatic adenocarcinoma (PDAC) is one of the most fatal malignancies. Surgical resection supplemented by chemotherapy remains the major therapeutic regimen, but with unavoidable resistance and systemic toxic reaction. Curcumin is a known safe natural compound that can effectively elimi...

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Detalles Bibliográficos
Autores principales: Cheng, Tao, Zhang, Zhiheng, Shen, Hua, Jian, Ziying, Li, Junsheng, Chen, Yujun, Shen, Yi, Dai, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487882/
https://www.ncbi.nlm.nih.gov/pubmed/32891174
http://dx.doi.org/10.1186/s12951-020-00687-2

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