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Undervirilized male infant with in utero exposure to maternal use of high dose antifungal therapy

BACKGROUND: Antifungals act on fungal sterols structurally similar to human cholesterol. Ketoconazole reversibly suppresses steroidogenesis by inhibiting cytochrome P450 enzymes and interferes with dihydrotestosterone (DHT) activity by binding to the androgen receptor. Hypospadias was reported in in...

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Detalles Bibliográficos
Autores principales:	Gujral, Jasmine, Costin, Gertrude, Khurana, Divya, Yau, Mabel, Wallach, Elizabeth, Romero, Christopher J., Wilkes, Meredith, Sethuram, Swathi, Rapaport, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488073/ https://www.ncbi.nlm.nih.gov/pubmed/32944019 http://dx.doi.org/10.1186/s13633-020-00087-1

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