Conditional ablation of MAPK7 expression in chondrocytes impairs endochondral bone formation in limbs and adaptation of chondrocytes to hypoxia

BACKGROUND: Long bones of limbs are formed through endochondral bone formation, which depends on the coordinated development of growth plates. Our previous studies have demonstrated that dysfunction of mitogen-activated protein kinase 7 (MAPK7) can cause skeletal dysplasia. However, little is known...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoming, Zhong, Dongmei, Gao, Wenjie, Liao, Zhiheng, Chen, Yuyu, Zhang, Shun, Zhou, Hang, Su, Peiqiang, Xu, Caixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488079/
https://www.ncbi.nlm.nih.gov/pubmed/32944217
http://dx.doi.org/10.1186/s13578-020-00462-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488079/
https://www.ncbi.nlm.nih.gov/pubmed/32944217
http://dx.doi.org/10.1186/s13578-020-00462-8

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