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Conditional ablation of MAPK7 expression in chondrocytes impairs endochondral bone formation in limbs and adaptation of chondrocytes to hypoxia

BACKGROUND: Long bones of limbs are formed through endochondral bone formation, which depends on the coordinated development of growth plates. Our previous studies have demonstrated that dysfunction of mitogen-activated protein kinase 7 (MAPK7) can cause skeletal dysplasia. However, little is known...

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Detalles Bibliográficos
Autores principales:	Yang, Xiaoming, Zhong, Dongmei, Gao, Wenjie, Liao, Zhiheng, Chen, Yuyu, Zhang, Shun, Zhou, Hang, Su, Peiqiang, Xu, Caixia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488079/ https://www.ncbi.nlm.nih.gov/pubmed/32944217 http://dx.doi.org/10.1186/s13578-020-00462-8

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