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Lithium intoxication–induced dysgeusia accompanied by glossalgia in a patient receiving lithium carbonate: a case report

BACKGROUND: Lithium carbonate is widely used as a first-line therapeutic agent for the depressive and manic phases of bipolar disorder. Although limb tremors and hypothyroidism are well-known side effects of lithium carbonate, other rare adverse reactions can also occur. CASE PRESENTATION: A 53-yea...

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Autores principales: Hanyu, Shota, Sugita, Naoko, Matsuda, Miyuki, Murai, Toshiya, Fujiwara, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488100/
https://www.ncbi.nlm.nih.gov/pubmed/32907624
http://dx.doi.org/10.1186/s13256-020-02495-6
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author Hanyu, Shota
Sugita, Naoko
Matsuda, Miyuki
Murai, Toshiya
Fujiwara, Hironobu
author_facet Hanyu, Shota
Sugita, Naoko
Matsuda, Miyuki
Murai, Toshiya
Fujiwara, Hironobu
author_sort Hanyu, Shota
collection PubMed
description BACKGROUND: Lithium carbonate is widely used as a first-line therapeutic agent for the depressive and manic phases of bipolar disorder. Although limb tremors and hypothyroidism are well-known side effects of lithium carbonate, other rare adverse reactions can also occur. CASE PRESENTATION: A 53-year-old Japanese woman diagnosed with lithium intoxication developed dysgeusia and glossalgia during treatment with lithium carbonate. She also showed symptoms of a swaying gait, finger tremors, and dysarthria. All of these symptoms subsided when her blood lithium concentration was reduced to a level below that which induces intoxication. CONCLUSIONS: We present a rare case of lithium carbonate–induced dysgeusia accompanied by glossalgia. Early detection of these symptoms is important in clinical settings because they can be overlooked until patients lose their appetite, which severely impairs their quality of life.
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spelling pubmed-74881002020-09-16 Lithium intoxication–induced dysgeusia accompanied by glossalgia in a patient receiving lithium carbonate: a case report Hanyu, Shota Sugita, Naoko Matsuda, Miyuki Murai, Toshiya Fujiwara, Hironobu J Med Case Rep Case Report BACKGROUND: Lithium carbonate is widely used as a first-line therapeutic agent for the depressive and manic phases of bipolar disorder. Although limb tremors and hypothyroidism are well-known side effects of lithium carbonate, other rare adverse reactions can also occur. CASE PRESENTATION: A 53-year-old Japanese woman diagnosed with lithium intoxication developed dysgeusia and glossalgia during treatment with lithium carbonate. She also showed symptoms of a swaying gait, finger tremors, and dysarthria. All of these symptoms subsided when her blood lithium concentration was reduced to a level below that which induces intoxication. CONCLUSIONS: We present a rare case of lithium carbonate–induced dysgeusia accompanied by glossalgia. Early detection of these symptoms is important in clinical settings because they can be overlooked until patients lose their appetite, which severely impairs their quality of life. BioMed Central 2020-09-10 /pmc/articles/PMC7488100/ /pubmed/32907624 http://dx.doi.org/10.1186/s13256-020-02495-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Hanyu, Shota
Sugita, Naoko
Matsuda, Miyuki
Murai, Toshiya
Fujiwara, Hironobu
Lithium intoxication–induced dysgeusia accompanied by glossalgia in a patient receiving lithium carbonate: a case report
title Lithium intoxication–induced dysgeusia accompanied by glossalgia in a patient receiving lithium carbonate: a case report
title_full Lithium intoxication–induced dysgeusia accompanied by glossalgia in a patient receiving lithium carbonate: a case report
title_fullStr Lithium intoxication–induced dysgeusia accompanied by glossalgia in a patient receiving lithium carbonate: a case report
title_full_unstemmed Lithium intoxication–induced dysgeusia accompanied by glossalgia in a patient receiving lithium carbonate: a case report
title_short Lithium intoxication–induced dysgeusia accompanied by glossalgia in a patient receiving lithium carbonate: a case report
title_sort lithium intoxication–induced dysgeusia accompanied by glossalgia in a patient receiving lithium carbonate: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488100/
https://www.ncbi.nlm.nih.gov/pubmed/32907624
http://dx.doi.org/10.1186/s13256-020-02495-6
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