Cargando…

Pellino-1 Regulates the Responses of the Airway to Viral Infection

Exposure to respiratory pathogens is a leading cause of exacerbations of airway diseases such as asthma and chronic obstructive pulmonary disease (COPD). Pellino-1 is an E3 ubiquitin ligase known to regulate virally-induced inflammation. We wished to determine the role of Pellino-1 in the host respo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marsh, Elizabeth K., Prestwich, Elizabeth C., Williams, Lynne, Hart, Amber R., Muir, Clare F., Parker, Lisa C., Jonker, Marnix R., Heijink, Irene H., Timens, Wim, Fife, Mark, Hussell, Tracy, Hershenson, Marc B., Bentley, J. Kelley, Sun, Shao-Cong, Barksby, Ben S., Borthwick, Lee A., Stewart, James P., Sabroe, Ian, Dockrell, David H., Marriott, Helen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488214/ https://www.ncbi.nlm.nih.gov/pubmed/32984077 http://dx.doi.org/10.3389/fcimb.2020.00456

Ejemplares similares

Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease
por: Hughes, Bethany M., et al.
Publicado: (2019)

Pellino Proteins in Viral Immunity and Pathogenesis
por: Jensen, Liselotte E.
Publicado: (2023)

Functional conservation of an ancestral Pellino protein in helminth species
por: Cluxton, Christopher D., et al.
Publicado: (2015)

The Emerging Roles of Pellino Family in Pattern Recognition Receptor Signaling
por: Zhang, E, et al.
Publicado: (2022)

LPS-induced Pellino3 degradation is mediated by p62-dependent autophagy
por: Heeg, A, et al.
Publicado: (2012)

Pellino Proteins: Novel Players in TLR and IL-1R Signalling
por: Schauvliege, Reinout, et al.
Publicado: (2007)

Human Rhinovirus Inhibits Macrophage Phagocytosis of Bacteria in Chronic Obstructive Pulmonary Disease. More Than a Common Cold
por: Sabroe, Ian, et al.
Publicado: (2019)

The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome
por: Humphries, Fiachra, et al.
Publicado: (2018)

miR-21 and Pellino-1 Expression Profiling in Autoimmune Premature Ovarian Insufficiency
por: Li, Xinran, et al.
Publicado: (2020)

Pellino1 deficiency reprograms cardiomyocytes energy metabolism in lipopolysaccharide-induced myocardial dysfunction
por: Yang, Chuanxi, et al.
Publicado: (2021)

Axl and MerTK receptor tyrosine kinases maintain human macrophage efferocytic capacity in the presence of viral triggers
por: Grabiec, Aleksander M, et al.
Publicado: (2018)

Pellino 1 inactivates mitotic spindle checkpoint by targeting BubR1 for ubiquitinational degradation
por: Park, Jihyun, et al.
Publicado: (2017)

Dendritic Cell–Specific Role for Pellino2 as a Mediator of TLR9 Signaling Pathway
por: Oleszycka, Ewa, et al.
Publicado: (2021)

The Pellino E3 Ubiquitin Ligases Recognize Specific Phosphothreonine Motifs and Have Distinct Substrate Specificities
por: Huoh, Yu-San, et al.
Publicado: (2014)

Insulin Resistance and Pellino-1 Mediated Decrease in the Activities of Vasodilator Signaling Contributes to Sunitinib-Induced Hypertension
por: Liu, Yang, et al.
Publicado: (2021)

IFNβ-Induced CXCL10 Chemokine Expression Is Regulated by Pellino3 Ligase in Monocytes and Macrophages
por: Makuch, Edyta, et al.
Publicado: (2022)

Pellino-1 promotes lung carcinogenesis via the stabilization of Slug and Snail through K63-mediated polyubiquitination
por: Jeon, Yoon Kyung, et al.
Publicado: (2017)

Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks
por: Ha, Geun-Hyoung, et al.
Publicado: (2019)

Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI
por: Hu, Bang-Chuan, et al.
Publicado: (2020)

Pellino1 promotes chronic inflammatory skin disease via keratinocyte hyperproliferation and induction of the T helper 17 response
por: Kim, Suhyeon, et al.
Publicado: (2020)

Ligase Pellino3 Regulates Macrophage Action and Survival in Response to VSV Infection in RIG-I-Dependent Path
por: Reniewicz, Patryk, et al.
Publicado: (2021)

Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD
por: Zandvoort, Andre, et al.
Publicado: (2008)

TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation
por: McGrath, Emmet E., et al.
Publicado: (2011)

DEAF1 Is a Pellino1-interacting Protein Required for Interferon Production by Sendai Virus and Double-stranded RNA
por: Ordureau, Alban, et al.
Publicado: (2013)

Dibutyl phthalate promotes juvenile Sertoli cell proliferation by decreasing the levels of the E3 ubiquitin ligase Pellino 2
por: Ma, Tan, et al.
Publicado: (2020)

Pellino1 promoted inflammation in lung injury model of sepsis by TRAF6/ NF-κB signal pathway
por: Liu, Xiaqing, et al.
Publicado: (2021)

Phosphoinositide-3 Kinase Inhibition Modulates Responses to Rhinovirus by Mechanisms that Are Predominantly Independent of Autophagy
por: Ismail, Saila, et al.
Publicado: (2014)

The Neutrophil
por: Dockrell, David H., et al.
Publicado: (2007)

Cell-surface localization of Pellino antagonizes Toll-mediated innate immune signalling by controlling MyD88 turnover in Drosophila
por: Ji, Shanming, et al.
Publicado: (2014)

Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination
por: Jeon, Yoon Kyung, et al.
Publicado: (2016)

miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1
por: Shang, Lin, et al.
Publicado: (2022)

Role of Pellino-1 in Inflammation and Cardioprotection following Severe Sepsis: A Novel Mechanism in a Murine Severe Sepsis Model †
por: Thirunavukkarasu, Mahesh, et al.
Publicado: (2023)

TGR5 activation attenuates neuroinflammation via Pellino3 inhibition of caspase-8/NLRP3 after middle cerebral artery occlusion in rats
por: Liang, Hui, et al.
Publicado: (2021)

Inhibition of β‐catenin/CBP signalling improves airway epithelial barrier function and suppresses CCL20 release
por: Kuchibhotla, Virinchi N. S., et al.
Publicado: (2020)

Deficient inflammasome activation permits an exaggerated asthma phenotype in rhinovirus C-infected immature mice
por: Han, Mingyuan, et al.
Publicado: (2021)

Macrophage Phenotype Is Associated with Disease Severity in Preterm Infants with Chronic Lung Disease
por: Prince, Lynne R., et al.
Publicado: (2014)

Resistomycin attenuates triple-negative breast cancer progression by inhibiting E3 ligase Pellino-1 and inducing SNAIL/SLUG degradation
por: Liu, Shan-shan, et al.
Publicado: (2020)

Pellino1 regulates neuropathic pain as well as microglial activation through the regulation of MAPK/NF-κB signaling in the spinal cord
por: Wang, Lijuan, et al.
Publicado: (2020)

K63 Ubiquitination of P21 Can Facilitate Pellino-1 in the Context of Chronic Obstructive Pulmonary Disease and Lung Cellular Senescence
por: Ma, Jia-Hui, et al.
Publicado: (2022)

Pellino 3 promotes the colitis‐associated colorectal cancer through suppression of IRF4‐mediated negative regulation of TLR4 signalling
por: Kim, Young‐Mi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_l5llu7g7qod702d503nlkf7fuo