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Metalign: efficient alignment-based metagenomic profiling via containment min hash
Metagenomic profiling, predicting the presence and relative abundances of microbes in a sample, is a critical first step in microbiome analysis. Alignment-based approaches are often considered accurate yet computationally infeasible. Here, we present a novel method, Metalign, that performs efficient...
Autores principales: | LaPierre, Nathan, Alser, Mohammed, Eskin, Eleazar, Koslicki, David, Mangul, Serghei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488264/ https://www.ncbi.nlm.nih.gov/pubmed/32912225 http://dx.doi.org/10.1186/s13059-020-02159-0 |
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