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Chemically defined human vascular laminins for biologically relevant culture of hiPSC-derived brain microvascular endothelial cells
BACKGROUND: In recent years, differentiation of human induced pluripotent stem cells (hiPSCs) into brain-specific microvascular endothelial cells (iBMECs) has frequently been used to model the blood–brain barrier (BBB). However, there are limitations in the use of iBMECs for in vitro studies, such a...
Autores principales: | Motallebnejad, Pedram, Azarin, Samira M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488267/ https://www.ncbi.nlm.nih.gov/pubmed/32912242 http://dx.doi.org/10.1186/s12987-020-00215-2 |
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