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LncRNA THRIL is upregulated in sepsis and sponges miR-19a to upregulate TNF-α in human bronchial epithelial cells

BACKGROUND: Long non-coding RNAs (lncRNAs) have been demonstrated to play critical roles in various diseases. Our bioinformatics analysis showed that lncRNA TNFα and heterogenous nuclear ribonucleoprotein L (hnRNPL) related immunoregulatory LincRNA (THRIL) may interact with miR-19a, which targets TN...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Liu, Jingbin, Tian, Chunhua, Wang, Hongyuan, Wen, Min, Yan, Mingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488348/
https://www.ncbi.nlm.nih.gov/pubmed/32944003
http://dx.doi.org/10.1186/s12950-020-00259-z