Disruption in iron homeostasis and impaired activity of iron-sulfur cluster containing proteins in the yeast model of Shwachman-Diamond syndrome

BACKGROUND: Shwachman-Diamond syndrome (SDS) is a congenital disease that affects the bone marrow, skeletal system, and pancreas. The majority of patients with SDS have mutations in the SBDS gene, involved in ribosome biogenesis as well as other processes. A Saccharomyces cerevisiae model of SDS, la...

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Detalles Bibliográficos
Autores principales: Jain, Ayushi, Nilatawong, Phubed, Mamak, Narinrat, Jensen, Laran T., Jensen, Amornrat Naranuntarat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488397/
https://www.ncbi.nlm.nih.gov/pubmed/32944219
http://dx.doi.org/10.1186/s13578-020-00468-2

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