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Human germline editing in the era of CRISPR-Cas: risk and uncertainty, inter-generational responsibility, therapeutic legitimacy

BACKGROUND: Clustered Regularly Interspaced Short Palindromic Repeats-associated (CRISPR-Cas) technology may allow for efficient and highly targeted gene editing in single-cell embryos. This possibility brings human germline editing into the focus of ethical and legal debates again. MAIN BODY: Again...

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Bibliographic Details
Main Authors: Schleidgen, Sebastian, Dederer, Hans-Georg, Sgodda, Susan, Cravcisin, Stefan, Lüneburg, Luca, Cantz, Tobias, Heinemann, Thomas
Format: Online Article Text
Language:English
Published: BioMed Central 2020
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488432/
https://www.ncbi.nlm.nih.gov/pubmed/32912206
http://dx.doi.org/10.1186/s12910-020-00487-1