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Histone Deacetylases Regulation by δ-Opioids in Human Optic Nerve Head Astrocytes
PURPOSE: We determined whether δ-opioid receptor agonist (SNC-121) regulates acetylation homeostasis via controlling histone deacetylases (HDACs) activity and expression in optic nerve head (ONH) astrocytes. METHODS: ONH astrocytes were treated with SNC-121 (1 µM) for 24 hours. The HDAC activity was...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488628/ https://www.ncbi.nlm.nih.gov/pubmed/32915982 http://dx.doi.org/10.1167/iovs.61.11.17 |