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Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection
BACKGROUND: Since the beginning of SARS-CoV-2 outbreak in China, severe acute respiratory syndrome has been widely descripted. Hemoptysis has rarely been observed in SARS-CoV-2 infection. We report here a case of severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infect...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488635/ https://www.ncbi.nlm.nih.gov/pubmed/32928157 http://dx.doi.org/10.1186/s12890-020-01285-6 |
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author | Lopinto, Julien Teulier, Marion Milon, Audrey Voiriot, Guillaume Fartoukh, Muriel |
author_facet | Lopinto, Julien Teulier, Marion Milon, Audrey Voiriot, Guillaume Fartoukh, Muriel |
author_sort | Lopinto, Julien |
collection | PubMed |
description | BACKGROUND: Since the beginning of SARS-CoV-2 outbreak in China, severe acute respiratory syndrome has been widely descripted. Hemoptysis has rarely been observed in SARS-CoV-2 infection. We report here a case of severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection and managed in a referral center. CASE PRESENTATION: A 58-year-old man was admitted to our intensive care unit for severe hemoptysis with history of post-tuberculosis bronchiectasis. At ICU admission the patient had fever and severe acute respiratory failure requiring high flow oxygen therapy. Respiratory tract sampling was positive for SARS-CoV-2. Multi-detector computed tomography angiography pointed out localized bronchiectasis on the left lower lobe and enlarged left bronchial and phrenic arteries; bronchial arteriography with distal embolization was performed with favorable outcome and no bleeding recurrence. CONCLUSIONS: To our knowledge, this is the first case of acute exacerbation of bronchiectasis related to SARS-CoV-2 infection and complicated by severe hemoptysis. Whether the virus may play a role in the dysregulation of airway haemostasis, and contribute to episodes of hemoptysis in patients with chronic pulmonary diseases and predisposing factors might be investigated. |
format | Online Article Text |
id | pubmed-7488635 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-74886352020-09-15 Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection Lopinto, Julien Teulier, Marion Milon, Audrey Voiriot, Guillaume Fartoukh, Muriel BMC Pulm Med Case Report BACKGROUND: Since the beginning of SARS-CoV-2 outbreak in China, severe acute respiratory syndrome has been widely descripted. Hemoptysis has rarely been observed in SARS-CoV-2 infection. We report here a case of severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection and managed in a referral center. CASE PRESENTATION: A 58-year-old man was admitted to our intensive care unit for severe hemoptysis with history of post-tuberculosis bronchiectasis. At ICU admission the patient had fever and severe acute respiratory failure requiring high flow oxygen therapy. Respiratory tract sampling was positive for SARS-CoV-2. Multi-detector computed tomography angiography pointed out localized bronchiectasis on the left lower lobe and enlarged left bronchial and phrenic arteries; bronchial arteriography with distal embolization was performed with favorable outcome and no bleeding recurrence. CONCLUSIONS: To our knowledge, this is the first case of acute exacerbation of bronchiectasis related to SARS-CoV-2 infection and complicated by severe hemoptysis. Whether the virus may play a role in the dysregulation of airway haemostasis, and contribute to episodes of hemoptysis in patients with chronic pulmonary diseases and predisposing factors might be investigated. BioMed Central 2020-09-14 /pmc/articles/PMC7488635/ /pubmed/32928157 http://dx.doi.org/10.1186/s12890-020-01285-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Lopinto, Julien Teulier, Marion Milon, Audrey Voiriot, Guillaume Fartoukh, Muriel Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection |
title | Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection |
title_full | Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection |
title_fullStr | Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection |
title_full_unstemmed | Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection |
title_short | Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection |
title_sort | severe hemoptysis in post-tuberculosis bronchiectasis precipitated by sars-cov-2 infection |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488635/ https://www.ncbi.nlm.nih.gov/pubmed/32928157 http://dx.doi.org/10.1186/s12890-020-01285-6 |
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