Cargando…

Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection

BACKGROUND: Since the beginning of SARS-CoV-2 outbreak in China, severe acute respiratory syndrome has been widely descripted. Hemoptysis has rarely been observed in SARS-CoV-2 infection. We report here a case of severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infect...

Descripción completa

Detalles Bibliográficos
Autores principales: Lopinto, Julien, Teulier, Marion, Milon, Audrey, Voiriot, Guillaume, Fartoukh, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488635/
https://www.ncbi.nlm.nih.gov/pubmed/32928157
http://dx.doi.org/10.1186/s12890-020-01285-6
_version_ 1783581732868456448
author Lopinto, Julien
Teulier, Marion
Milon, Audrey
Voiriot, Guillaume
Fartoukh, Muriel
author_facet Lopinto, Julien
Teulier, Marion
Milon, Audrey
Voiriot, Guillaume
Fartoukh, Muriel
author_sort Lopinto, Julien
collection PubMed
description BACKGROUND: Since the beginning of SARS-CoV-2 outbreak in China, severe acute respiratory syndrome has been widely descripted. Hemoptysis has rarely been observed in SARS-CoV-2 infection. We report here a case of severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection and managed in a referral center. CASE PRESENTATION: A 58-year-old man was admitted to our intensive care unit for severe hemoptysis with history of post-tuberculosis bronchiectasis. At ICU admission the patient had fever and severe acute respiratory failure requiring high flow oxygen therapy. Respiratory tract sampling was positive for SARS-CoV-2. Multi-detector computed tomography angiography pointed out localized bronchiectasis on the left lower lobe and enlarged left bronchial and phrenic arteries; bronchial arteriography with distal embolization was performed with favorable outcome and no bleeding recurrence. CONCLUSIONS: To our knowledge, this is the first case of acute exacerbation of bronchiectasis related to SARS-CoV-2 infection and complicated by severe hemoptysis. Whether the virus may play a role in the dysregulation of airway haemostasis, and contribute to episodes of hemoptysis in patients with chronic pulmonary diseases and predisposing factors might be investigated.
format Online
Article
Text
id pubmed-7488635
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-74886352020-09-15 Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection Lopinto, Julien Teulier, Marion Milon, Audrey Voiriot, Guillaume Fartoukh, Muriel BMC Pulm Med Case Report BACKGROUND: Since the beginning of SARS-CoV-2 outbreak in China, severe acute respiratory syndrome has been widely descripted. Hemoptysis has rarely been observed in SARS-CoV-2 infection. We report here a case of severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection and managed in a referral center. CASE PRESENTATION: A 58-year-old man was admitted to our intensive care unit for severe hemoptysis with history of post-tuberculosis bronchiectasis. At ICU admission the patient had fever and severe acute respiratory failure requiring high flow oxygen therapy. Respiratory tract sampling was positive for SARS-CoV-2. Multi-detector computed tomography angiography pointed out localized bronchiectasis on the left lower lobe and enlarged left bronchial and phrenic arteries; bronchial arteriography with distal embolization was performed with favorable outcome and no bleeding recurrence. CONCLUSIONS: To our knowledge, this is the first case of acute exacerbation of bronchiectasis related to SARS-CoV-2 infection and complicated by severe hemoptysis. Whether the virus may play a role in the dysregulation of airway haemostasis, and contribute to episodes of hemoptysis in patients with chronic pulmonary diseases and predisposing factors might be investigated. BioMed Central 2020-09-14 /pmc/articles/PMC7488635/ /pubmed/32928157 http://dx.doi.org/10.1186/s12890-020-01285-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Lopinto, Julien
Teulier, Marion
Milon, Audrey
Voiriot, Guillaume
Fartoukh, Muriel
Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection
title Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection
title_full Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection
title_fullStr Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection
title_full_unstemmed Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection
title_short Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection
title_sort severe hemoptysis in post-tuberculosis bronchiectasis precipitated by sars-cov-2 infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488635/
https://www.ncbi.nlm.nih.gov/pubmed/32928157
http://dx.doi.org/10.1186/s12890-020-01285-6
work_keys_str_mv AT lopintojulien severehemoptysisinposttuberculosisbronchiectasisprecipitatedbysarscov2infection
AT teuliermarion severehemoptysisinposttuberculosisbronchiectasisprecipitatedbysarscov2infection
AT milonaudrey severehemoptysisinposttuberculosisbronchiectasisprecipitatedbysarscov2infection
AT voiriotguillaume severehemoptysisinposttuberculosisbronchiectasisprecipitatedbysarscov2infection
AT fartoukhmuriel severehemoptysisinposttuberculosisbronchiectasisprecipitatedbysarscov2infection