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Epigenetic loci for blood pressure are associated with hypertensive target organ damage in older African Americans from the genetic epidemiology network of Arteriopathy (GENOA) study
BACKGROUND: Hypertension is a major modifiable risk factor for arteriosclerosis that can lead to target organ damage (TOD) of heart, kidneys, and peripheral arteries. A recent epigenome-wide association study for blood pressure (BP) identified 13 CpG sites, but it is not known whether DNA methylatio...
Autores principales: | Kho, Minjung, Zhao, Wei, Ratliff, Scott M., Ammous, Farah, Mosley, Thomas H., Shang, Lulu, Kardia, Sharon L. R., Zhou, Xiang, Smith, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488710/ https://www.ncbi.nlm.nih.gov/pubmed/32917208 http://dx.doi.org/10.1186/s12920-020-00791-0 |
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