Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies

Recent long-read assemblies often exceed the quality and completeness of available reference genomes, making validation challenging. Here we present Merqury, a novel tool for reference-free assembly evaluation based on efficient k-mer set operations. By comparing k-mers in a de novo assembly to thos...

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Detalles Bibliográficos
Autores principales: Rhie, Arang, Walenz, Brian P., Koren, Sergey, Phillippy, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488777/
https://www.ncbi.nlm.nih.gov/pubmed/32928274
http://dx.doi.org/10.1186/s13059-020-02134-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488777/
https://www.ncbi.nlm.nih.gov/pubmed/32928274
http://dx.doi.org/10.1186/s13059-020-02134-9

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