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Interleukin-37 contributes to the pathogenesis of gout by affecting PDZ domain-containing 1 protein through the nuclear factor-kappa B pathway

OBJECTIVE: Our objective was to explore the molecular pathogenesis of the onset of gout and the mechanism underlying the effect of interleukin (IL)-37 on PDZ domain-containing 1 (PDZK1) protein through the nuclear factor-κB signaling pathway. METHODS: Real-time PCR and western blotting were used to...

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Detalles Bibliográficos
Autores principales: Wan, Wei, Shi, Yeqing, Ji, Lianmei, Li, Xiaofang, Xu, Xia, Zhao, Dongbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488913/
https://www.ncbi.nlm.nih.gov/pubmed/32910705
http://dx.doi.org/10.1177/0300060520948717