Cargando…
Ethics of research on stem cells and regenerative medicine: ethical guidelines in the Islamic Republic of Iran
BACKGROUND: Regenerative medicine plays a major role in biomedicine, and given the ever-expanding boundaries of this knowledge, numerous ethical considerations have been raised. MAIN TEXT: Rapid advancement of regenerative medicine science and technology in Iran, emerged the Iranian National Committ...
| Autores principales: | , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489032/ https://www.ncbi.nlm.nih.gov/pubmed/32928295 http://dx.doi.org/10.1186/s13287-020-01916-z |
| _version_ | 1783581808658481152 |
|---|---|
| author | Afshar, Leila Aghayan, Hamid-Reza Sadighi, Jila Arjmand, Babak Hashemi, Seyed-Mahmoud Basiri, Mohsen Samani, Reza Omani Ashtiani, Mohammad Kazemi Azin, Seyed-Ali Hajizadeh-Saffar, Ensiyeh Gooshki, Ehsan Shamsi Hamidieh, Amir-Ali Rezania Moallem, Mohammad-Reza Azin, Seyed-Mohammad Shariatinasab, Sadegh Soleymani-Goloujeh, Mehdi Baharvand, Hossein |
| author_facet | Afshar, Leila Aghayan, Hamid-Reza Sadighi, Jila Arjmand, Babak Hashemi, Seyed-Mahmoud Basiri, Mohsen Samani, Reza Omani Ashtiani, Mohammad Kazemi Azin, Seyed-Ali Hajizadeh-Saffar, Ensiyeh Gooshki, Ehsan Shamsi Hamidieh, Amir-Ali Rezania Moallem, Mohammad-Reza Azin, Seyed-Mohammad Shariatinasab, Sadegh Soleymani-Goloujeh, Mehdi Baharvand, Hossein |
| author_sort | Afshar, Leila |
| collection | PubMed |
| description | BACKGROUND: Regenerative medicine plays a major role in biomedicine, and given the ever-expanding boundaries of this knowledge, numerous ethical considerations have been raised. MAIN TEXT: Rapid advancement of regenerative medicine science and technology in Iran, emerged the Iranian National Committee for Ethics in Biomedical Research to develop a comprehensive national ethical guideline. Therefore, the present ethical guideline which comprises eleven chapters was developed in 2019 and approved in early 2020. The titles of these chapters were selected based on the ethical considerations of various aspects of the field of regenerative medicine: (1) ethical principles of research on stem cells and regenerative medicine; (2) ethical considerations for research on stem cells (embryonic stem cells, epiblast stem cells, tissue-specific stem cells, stem cells derived from transdifferentiation, induced pluripotent stem cells [iPSCs], germline pluripotent stem cells, germline stem cells, and somatic cell nuclear transfer [SCNT] stem cells); (3) ethical considerations for research on somatic cells in regenerative medicine (adult somatic cells, fetal tissue somatic cells, and somatic cells derived from pregnancy products [other than fetus]); (4) ethical considerations for research on gametes in regenerative medicine; (5) ethical considerations for research related to genetic manipulation (human and animal) in regenerative medicine; (6) ethical considerations for research on tissue engineering in regenerative medicine; (7) ethical considerations for pre-clinical studies in regenerative medicine; (8) ethical considerations for clinical trials in regenerative medicine; (9) ethical considerations for stem cells and regenerative medicine bio-banks; (10) ethical considerations for privacy and confidentiality; and (11) ethical considerations for obtaining informed consent. CONCLUSION: This article discusses the process of developing the present ethical guidelines and its practical points. We hope that it can play an important worldwide role in advancing ethics of research on stem cells and regenerative medicine. |
| format | Online Article Text |
| id | pubmed-7489032 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-74890322020-09-16 Ethics of research on stem cells and regenerative medicine: ethical guidelines in the Islamic Republic of Iran Afshar, Leila Aghayan, Hamid-Reza Sadighi, Jila Arjmand, Babak Hashemi, Seyed-Mahmoud Basiri, Mohsen Samani, Reza Omani Ashtiani, Mohammad Kazemi Azin, Seyed-Ali Hajizadeh-Saffar, Ensiyeh Gooshki, Ehsan Shamsi Hamidieh, Amir-Ali Rezania Moallem, Mohammad-Reza Azin, Seyed-Mohammad Shariatinasab, Sadegh Soleymani-Goloujeh, Mehdi Baharvand, Hossein Stem Cell Res Ther Commentary BACKGROUND: Regenerative medicine plays a major role in biomedicine, and given the ever-expanding boundaries of this knowledge, numerous ethical considerations have been raised. MAIN TEXT: Rapid advancement of regenerative medicine science and technology in Iran, emerged the Iranian National Committee for Ethics in Biomedical Research to develop a comprehensive national ethical guideline. Therefore, the present ethical guideline which comprises eleven chapters was developed in 2019 and approved in early 2020. The titles of these chapters were selected based on the ethical considerations of various aspects of the field of regenerative medicine: (1) ethical principles of research on stem cells and regenerative medicine; (2) ethical considerations for research on stem cells (embryonic stem cells, epiblast stem cells, tissue-specific stem cells, stem cells derived from transdifferentiation, induced pluripotent stem cells [iPSCs], germline pluripotent stem cells, germline stem cells, and somatic cell nuclear transfer [SCNT] stem cells); (3) ethical considerations for research on somatic cells in regenerative medicine (adult somatic cells, fetal tissue somatic cells, and somatic cells derived from pregnancy products [other than fetus]); (4) ethical considerations for research on gametes in regenerative medicine; (5) ethical considerations for research related to genetic manipulation (human and animal) in regenerative medicine; (6) ethical considerations for research on tissue engineering in regenerative medicine; (7) ethical considerations for pre-clinical studies in regenerative medicine; (8) ethical considerations for clinical trials in regenerative medicine; (9) ethical considerations for stem cells and regenerative medicine bio-banks; (10) ethical considerations for privacy and confidentiality; and (11) ethical considerations for obtaining informed consent. CONCLUSION: This article discusses the process of developing the present ethical guidelines and its practical points. We hope that it can play an important worldwide role in advancing ethics of research on stem cells and regenerative medicine. BioMed Central 2020-09-14 /pmc/articles/PMC7489032/ /pubmed/32928295 http://dx.doi.org/10.1186/s13287-020-01916-z Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
| spellingShingle | Commentary Afshar, Leila Aghayan, Hamid-Reza Sadighi, Jila Arjmand, Babak Hashemi, Seyed-Mahmoud Basiri, Mohsen Samani, Reza Omani Ashtiani, Mohammad Kazemi Azin, Seyed-Ali Hajizadeh-Saffar, Ensiyeh Gooshki, Ehsan Shamsi Hamidieh, Amir-Ali Rezania Moallem, Mohammad-Reza Azin, Seyed-Mohammad Shariatinasab, Sadegh Soleymani-Goloujeh, Mehdi Baharvand, Hossein Ethics of research on stem cells and regenerative medicine: ethical guidelines in the Islamic Republic of Iran |
| title | Ethics of research on stem cells and regenerative medicine: ethical guidelines in the Islamic Republic of Iran |
| title_full | Ethics of research on stem cells and regenerative medicine: ethical guidelines in the Islamic Republic of Iran |
| title_fullStr | Ethics of research on stem cells and regenerative medicine: ethical guidelines in the Islamic Republic of Iran |
| title_full_unstemmed | Ethics of research on stem cells and regenerative medicine: ethical guidelines in the Islamic Republic of Iran |
| title_short | Ethics of research on stem cells and regenerative medicine: ethical guidelines in the Islamic Republic of Iran |
| title_sort | ethics of research on stem cells and regenerative medicine: ethical guidelines in the islamic republic of iran |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489032/ https://www.ncbi.nlm.nih.gov/pubmed/32928295 http://dx.doi.org/10.1186/s13287-020-01916-z |
| work_keys_str_mv | AT afsharleila ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT aghayanhamidreza ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT sadighijila ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT arjmandbabak ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT hashemiseyedmahmoud ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT basirimohsen ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT samanirezaomani ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT ashtianimohammadkazemi ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT azinseyedali ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT hajizadehsaffarensiyeh ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT gooshkiehsanshamsi ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT hamidiehamirali ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT rezaniamoallemmohammadreza ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT azinseyedmohammad ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT shariatinasabsadegh ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT soleymanigoloujehmehdi ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran AT baharvandhossein ethicsofresearchonstemcellsandregenerativemedicineethicalguidelinesintheislamicrepublicofiran |