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MicroRNA-34c Inhibits Osteogenic Differentiation and Valvular Interstitial Cell Calcification via STC1-Mediated JNK Pathway in Calcific Aortic Valve Disease
Calcific aortic valve disease (CAVD), a common heart valve disease, is increasingly prevalent worldwide and causes high morbidity and mortality. Here, we aimed to investigate a possible role for miR-34c in the development of osteogenic differentiation during CAVD and to find out the underlying mecha...
Autores principales: | Yang, Lieming, Zhu, Xinyuan, Ni, Yingying, Wu, Dawei, Tian, Yikui, Chen, Zhi, Li, Mingbiao, Zhang, Hao, Liang, Degang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489094/ https://www.ncbi.nlm.nih.gov/pubmed/32982764 http://dx.doi.org/10.3389/fphys.2020.00829 |
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