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Association Between Psoriasis and Depression: A Traditional Review
Psoriasis is a chronic inflammatory disease of the skin with multiple comorbidities, depression being one of them. Psoriasis affects the personal, social, and sexual lives of the patients resulting in psychological strain. Psoriasis and depression amplify each other. Supporting evidence has proven ...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489316/ https://www.ncbi.nlm.nih.gov/pubmed/32944430 http://dx.doi.org/10.7759/cureus.9708 |
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author | Sahi, Faryal Mustansir Masood, Ayesha Danawar, Nuaman A Mekaiel, Andrew Malik, Bilal Haider |
author_facet | Sahi, Faryal Mustansir Masood, Ayesha Danawar, Nuaman A Mekaiel, Andrew Malik, Bilal Haider |
author_sort | Sahi, Faryal Mustansir |
collection | PubMed |
description | Psoriasis is a chronic inflammatory disease of the skin with multiple comorbidities, depression being one of them. Psoriasis affects the personal, social, and sexual lives of the patients resulting in psychological strain. Psoriasis and depression amplify each other. Supporting evidence has proven multiple common mechanisms between the two diseases: inflammatory overlap, genetic evidence, low vitamin D3, and melatonin levels are common in both psoriasis and depression. Fear of social rejection and self-stigmatization act as a fuel to fire inflaming depression in psoriatic patients. The study explains the link between psoriasis and depression and their effects on quality of life. There is a need to highlight the importance of addressing the psychological effects of psoriasis along with its physical aspects for better treatment outcomes. |
format | Online Article Text |
id | pubmed-7489316 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-74893162020-09-16 Association Between Psoriasis and Depression: A Traditional Review Sahi, Faryal Mustansir Masood, Ayesha Danawar, Nuaman A Mekaiel, Andrew Malik, Bilal Haider Cureus Dermatology Psoriasis is a chronic inflammatory disease of the skin with multiple comorbidities, depression being one of them. Psoriasis affects the personal, social, and sexual lives of the patients resulting in psychological strain. Psoriasis and depression amplify each other. Supporting evidence has proven multiple common mechanisms between the two diseases: inflammatory overlap, genetic evidence, low vitamin D3, and melatonin levels are common in both psoriasis and depression. Fear of social rejection and self-stigmatization act as a fuel to fire inflaming depression in psoriatic patients. The study explains the link between psoriasis and depression and their effects on quality of life. There is a need to highlight the importance of addressing the psychological effects of psoriasis along with its physical aspects for better treatment outcomes. Cureus 2020-08-13 /pmc/articles/PMC7489316/ /pubmed/32944430 http://dx.doi.org/10.7759/cureus.9708 Text en Copyright © 2020, Sahi et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Dermatology Sahi, Faryal Mustansir Masood, Ayesha Danawar, Nuaman A Mekaiel, Andrew Malik, Bilal Haider Association Between Psoriasis and Depression: A Traditional Review |
title | Association Between Psoriasis and Depression: A Traditional Review |
title_full | Association Between Psoriasis and Depression: A Traditional Review |
title_fullStr | Association Between Psoriasis and Depression: A Traditional Review |
title_full_unstemmed | Association Between Psoriasis and Depression: A Traditional Review |
title_short | Association Between Psoriasis and Depression: A Traditional Review |
title_sort | association between psoriasis and depression: a traditional review |
topic | Dermatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489316/ https://www.ncbi.nlm.nih.gov/pubmed/32944430 http://dx.doi.org/10.7759/cureus.9708 |
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