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Association Between Psoriasis and Depression: A Traditional Review

Psoriasis is a chronic inflammatory disease of the skin with multiple comorbidities, depression being one of them. Psoriasis affects the personal, social, and sexual lives of the patients resulting in psychological strain.  Psoriasis and depression amplify each other. Supporting evidence has proven ...

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Autores principales: Sahi, Faryal Mustansir, Masood, Ayesha, Danawar, Nuaman A, Mekaiel, Andrew, Malik, Bilal Haider
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489316/
https://www.ncbi.nlm.nih.gov/pubmed/32944430
http://dx.doi.org/10.7759/cureus.9708
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author Sahi, Faryal Mustansir
Masood, Ayesha
Danawar, Nuaman A
Mekaiel, Andrew
Malik, Bilal Haider
author_facet Sahi, Faryal Mustansir
Masood, Ayesha
Danawar, Nuaman A
Mekaiel, Andrew
Malik, Bilal Haider
author_sort Sahi, Faryal Mustansir
collection PubMed
description Psoriasis is a chronic inflammatory disease of the skin with multiple comorbidities, depression being one of them. Psoriasis affects the personal, social, and sexual lives of the patients resulting in psychological strain.  Psoriasis and depression amplify each other. Supporting evidence has proven multiple common mechanisms between the two diseases: inflammatory overlap, genetic evidence, low vitamin D3, and melatonin levels are common in both psoriasis and depression. Fear of social rejection and self-stigmatization act as a fuel to fire inflaming depression in psoriatic patients. The study explains the link between psoriasis and depression and their effects on quality of life. There is a need to highlight the importance of addressing the psychological effects of psoriasis along with its physical aspects for better treatment outcomes. 
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spelling pubmed-74893162020-09-16 Association Between Psoriasis and Depression: A Traditional Review Sahi, Faryal Mustansir Masood, Ayesha Danawar, Nuaman A Mekaiel, Andrew Malik, Bilal Haider Cureus Dermatology Psoriasis is a chronic inflammatory disease of the skin with multiple comorbidities, depression being one of them. Psoriasis affects the personal, social, and sexual lives of the patients resulting in psychological strain.  Psoriasis and depression amplify each other. Supporting evidence has proven multiple common mechanisms between the two diseases: inflammatory overlap, genetic evidence, low vitamin D3, and melatonin levels are common in both psoriasis and depression. Fear of social rejection and self-stigmatization act as a fuel to fire inflaming depression in psoriatic patients. The study explains the link between psoriasis and depression and their effects on quality of life. There is a need to highlight the importance of addressing the psychological effects of psoriasis along with its physical aspects for better treatment outcomes.  Cureus 2020-08-13 /pmc/articles/PMC7489316/ /pubmed/32944430 http://dx.doi.org/10.7759/cureus.9708 Text en Copyright © 2020, Sahi et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Sahi, Faryal Mustansir
Masood, Ayesha
Danawar, Nuaman A
Mekaiel, Andrew
Malik, Bilal Haider
Association Between Psoriasis and Depression: A Traditional Review
title Association Between Psoriasis and Depression: A Traditional Review
title_full Association Between Psoriasis and Depression: A Traditional Review
title_fullStr Association Between Psoriasis and Depression: A Traditional Review
title_full_unstemmed Association Between Psoriasis and Depression: A Traditional Review
title_short Association Between Psoriasis and Depression: A Traditional Review
title_sort association between psoriasis and depression: a traditional review
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489316/
https://www.ncbi.nlm.nih.gov/pubmed/32944430
http://dx.doi.org/10.7759/cureus.9708
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