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Role of Hypofractionated Stereotactic Radiosurgery in Recurrent Pineal Parenchymal Tumors of Intermediate Differentiation: A Case Report and Review of the Literature

A pineal parenchymal tumor of intermediate differentiation (PPID) is a rare entity, and optimal treatment is still unclear. Combined multimodality treatment should be considered in PPID due to high recurrence rates. Gross total resection is the first choice of treatment, however, it may not be feasi...

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Detalles Bibliográficos
Autores principales: Beduk Esen, Caglayan Selenge, Yazici, Gozde, Berker, Mustafa, Zorlu, Faruk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489324/
https://www.ncbi.nlm.nih.gov/pubmed/32944431
http://dx.doi.org/10.7759/cureus.9709
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author Beduk Esen, Caglayan Selenge
Yazici, Gozde
Berker, Mustafa
Zorlu, Faruk
author_facet Beduk Esen, Caglayan Selenge
Yazici, Gozde
Berker, Mustafa
Zorlu, Faruk
author_sort Beduk Esen, Caglayan Selenge
collection PubMed
description A pineal parenchymal tumor of intermediate differentiation (PPID) is a rare entity, and optimal treatment is still unclear. Combined multimodality treatment should be considered in PPID due to high recurrence rates. Gross total resection is the first choice of treatment, however, it may not be feasible in every case due to location. Stereotactic radiosurgery (SRS) can be considered for the treatment of primary and recurrent disease, as it enables us to deliver a high radiation dose to the target while minimizing radiation exposure to normal tissue. In this report, we present a case treated with hypofractionated SRS for recurrent/metastatic PPID after the primary tumor was controlled with the combination of surgery and conventionally fractionated radiotherapy.
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spelling pubmed-74893242020-09-16 Role of Hypofractionated Stereotactic Radiosurgery in Recurrent Pineal Parenchymal Tumors of Intermediate Differentiation: A Case Report and Review of the Literature Beduk Esen, Caglayan Selenge Yazici, Gozde Berker, Mustafa Zorlu, Faruk Cureus Radiation Oncology A pineal parenchymal tumor of intermediate differentiation (PPID) is a rare entity, and optimal treatment is still unclear. Combined multimodality treatment should be considered in PPID due to high recurrence rates. Gross total resection is the first choice of treatment, however, it may not be feasible in every case due to location. Stereotactic radiosurgery (SRS) can be considered for the treatment of primary and recurrent disease, as it enables us to deliver a high radiation dose to the target while minimizing radiation exposure to normal tissue. In this report, we present a case treated with hypofractionated SRS for recurrent/metastatic PPID after the primary tumor was controlled with the combination of surgery and conventionally fractionated radiotherapy. Cureus 2020-08-13 /pmc/articles/PMC7489324/ /pubmed/32944431 http://dx.doi.org/10.7759/cureus.9709 Text en Copyright © 2020, Beduk Esen et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiation Oncology
Beduk Esen, Caglayan Selenge
Yazici, Gozde
Berker, Mustafa
Zorlu, Faruk
Role of Hypofractionated Stereotactic Radiosurgery in Recurrent Pineal Parenchymal Tumors of Intermediate Differentiation: A Case Report and Review of the Literature
title Role of Hypofractionated Stereotactic Radiosurgery in Recurrent Pineal Parenchymal Tumors of Intermediate Differentiation: A Case Report and Review of the Literature
title_full Role of Hypofractionated Stereotactic Radiosurgery in Recurrent Pineal Parenchymal Tumors of Intermediate Differentiation: A Case Report and Review of the Literature
title_fullStr Role of Hypofractionated Stereotactic Radiosurgery in Recurrent Pineal Parenchymal Tumors of Intermediate Differentiation: A Case Report and Review of the Literature
title_full_unstemmed Role of Hypofractionated Stereotactic Radiosurgery in Recurrent Pineal Parenchymal Tumors of Intermediate Differentiation: A Case Report and Review of the Literature
title_short Role of Hypofractionated Stereotactic Radiosurgery in Recurrent Pineal Parenchymal Tumors of Intermediate Differentiation: A Case Report and Review of the Literature
title_sort role of hypofractionated stereotactic radiosurgery in recurrent pineal parenchymal tumors of intermediate differentiation: a case report and review of the literature
topic Radiation Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489324/
https://www.ncbi.nlm.nih.gov/pubmed/32944431
http://dx.doi.org/10.7759/cureus.9709
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