A Systematic, Unbiased Mapping of CD8(+) and CD4(+) T Cell Epitopes in Yellow Fever Vaccinees

Examining CD8(+) and CD4(+) T cell responses after primary Yellow Fever vaccination in a cohort of 210 volunteers, we have identified and tetramer-validated 92 CD8(+) and 50 CD4(+) T cell epitopes, many inducing strong and prevalent (i.e., immunodominant) T cell responses. Restricted by 40 and 14 HL...

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Detalles Bibliográficos
Autores principales: Stryhn, Anette, Kongsgaard, Michael, Rasmussen, Michael, Harndahl, Mikkel Nors, Østerbye, Thomas, Bassi, Maria Rosaria, Thybo, Søren, Gabriel, Mette, Hansen, Morten Bagge, Nielsen, Morten, Christensen, Jan Pravsgaard, Randrup Thomsen, Allan, Buus, Soren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489334/
https://www.ncbi.nlm.nih.gov/pubmed/32983097
http://dx.doi.org/10.3389/fimmu.2020.01836

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