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The prognostic value of geriatric nutritional risk index in elderly patients with severe community-acquired pneumonia: A retrospective study

The geriatric nutritional risk index (GNRI) is associated with the prognosis of many diseases. However, the association between the GNRI and the prognosis of patients aged ≥65 years with severe community-acquired pneumonia (SCAP) has not been studied. We aimed to evaluate the prognostic value of GNR...

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Autores principales: Wei, Lishuang, Xie, Hailun, Li, Junkang, Li, Rui, Chen, Weijian, Huang, Lanfang, Li, Xialin, Yan, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489621/
https://www.ncbi.nlm.nih.gov/pubmed/32925799
http://dx.doi.org/10.1097/MD.0000000000022217
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author Wei, Lishuang
Xie, Hailun
Li, Junkang
Li, Rui
Chen, Weijian
Huang, Lanfang
Li, Xialin
Yan, Ping
author_facet Wei, Lishuang
Xie, Hailun
Li, Junkang
Li, Rui
Chen, Weijian
Huang, Lanfang
Li, Xialin
Yan, Ping
author_sort Wei, Lishuang
collection PubMed
description The geriatric nutritional risk index (GNRI) is associated with the prognosis of many diseases. However, the association between the GNRI and the prognosis of patients aged ≥65 years with severe community-acquired pneumonia (SCAP) has not been studied. We aimed to evaluate the prognostic value of GNRI in elderly SCAP patients. This study retrospectively analyzed the clinical data of 346 patients aged ≥65 years with SCAP from December 2013 to September 2019. Patients were divided into 4 groups by the GNRI. The chi-square test or student's t test was used to compare the differences between the groups. Logistic regression analysis was used to evaluate the factors that affect prognosis. The receiver operating characteristic curve was used to compare the prognostic performance of the GNRI with other indicators. A GNRI-based nomogram was established based on the result of the multivariate analysis. Two hundred nine (60.4%) patients had a poor prognosis. GNRI scores were significantly lower in the poor prognosis group than in the group with a good prognosis. In the multivariate analysis, gender, mean arterial pressure, neutrophil counts, and the GNRI were independently correlated with the prognosis of elderly patients. The GNRI was a significantly better predictor for poor prognosis than other indicators. The GNRI-based nomogram had excellent prediction capabilities. GNRI is a simple and effective prognostic indicator for elderly patients with SCAP, and a GNRI-based nomogram can aid in developing individualized treatment plans for elderly patients with SCAP.
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spelling pubmed-74896212020-09-24 The prognostic value of geriatric nutritional risk index in elderly patients with severe community-acquired pneumonia: A retrospective study Wei, Lishuang Xie, Hailun Li, Junkang Li, Rui Chen, Weijian Huang, Lanfang Li, Xialin Yan, Ping Medicine (Baltimore) 6700 The geriatric nutritional risk index (GNRI) is associated with the prognosis of many diseases. However, the association between the GNRI and the prognosis of patients aged ≥65 years with severe community-acquired pneumonia (SCAP) has not been studied. We aimed to evaluate the prognostic value of GNRI in elderly SCAP patients. This study retrospectively analyzed the clinical data of 346 patients aged ≥65 years with SCAP from December 2013 to September 2019. Patients were divided into 4 groups by the GNRI. The chi-square test or student's t test was used to compare the differences between the groups. Logistic regression analysis was used to evaluate the factors that affect prognosis. The receiver operating characteristic curve was used to compare the prognostic performance of the GNRI with other indicators. A GNRI-based nomogram was established based on the result of the multivariate analysis. Two hundred nine (60.4%) patients had a poor prognosis. GNRI scores were significantly lower in the poor prognosis group than in the group with a good prognosis. In the multivariate analysis, gender, mean arterial pressure, neutrophil counts, and the GNRI were independently correlated with the prognosis of elderly patients. The GNRI was a significantly better predictor for poor prognosis than other indicators. The GNRI-based nomogram had excellent prediction capabilities. GNRI is a simple and effective prognostic indicator for elderly patients with SCAP, and a GNRI-based nomogram can aid in developing individualized treatment plans for elderly patients with SCAP. Lippincott Williams & Wilkins 2020-09-11 /pmc/articles/PMC7489621/ /pubmed/32925799 http://dx.doi.org/10.1097/MD.0000000000022217 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 6700
Wei, Lishuang
Xie, Hailun
Li, Junkang
Li, Rui
Chen, Weijian
Huang, Lanfang
Li, Xialin
Yan, Ping
The prognostic value of geriatric nutritional risk index in elderly patients with severe community-acquired pneumonia: A retrospective study
title The prognostic value of geriatric nutritional risk index in elderly patients with severe community-acquired pneumonia: A retrospective study
title_full The prognostic value of geriatric nutritional risk index in elderly patients with severe community-acquired pneumonia: A retrospective study
title_fullStr The prognostic value of geriatric nutritional risk index in elderly patients with severe community-acquired pneumonia: A retrospective study
title_full_unstemmed The prognostic value of geriatric nutritional risk index in elderly patients with severe community-acquired pneumonia: A retrospective study
title_short The prognostic value of geriatric nutritional risk index in elderly patients with severe community-acquired pneumonia: A retrospective study
title_sort prognostic value of geriatric nutritional risk index in elderly patients with severe community-acquired pneumonia: a retrospective study
topic 6700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489621/
https://www.ncbi.nlm.nih.gov/pubmed/32925799
http://dx.doi.org/10.1097/MD.0000000000022217
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