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Effects and safety of Tanreqing injection on viral pneumonia: A protocol for systematic review and meta-analysis

BACKGROUND: Influenza-related viral pneumonia is a severe threat to human health, which has caused high morbidity and mortality each year. The objective of this study was to assess the efficacy and safety of Tanreqing Injection therapy in patients with viral pneumonia. MATERIALS AND METHODS: This pr...

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Detalles Bibliográficos
Autores principales: Qiu, Yue, Pan, Xue, Su, Lin, Lui, Hui, Li, Ya-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489681/
https://www.ncbi.nlm.nih.gov/pubmed/32925736
http://dx.doi.org/10.1097/MD.0000000000022022
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author Qiu, Yue
Pan, Xue
Su, Lin
Lui, Hui
Li, Ya-Dong
author_facet Qiu, Yue
Pan, Xue
Su, Lin
Lui, Hui
Li, Ya-Dong
author_sort Qiu, Yue
collection PubMed
description BACKGROUND: Influenza-related viral pneumonia is a severe threat to human health, which has caused high morbidity and mortality each year. The objective of this study was to assess the efficacy and safety of Tanreqing Injection therapy in patients with viral pneumonia. MATERIALS AND METHODS: This protocol established in this study has been reported following the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols. Web of Science, PubMed, EMBASE and the Cochrane Library were searched for clinical randomized trials in cases with viral pneumonia until 1st of July 2020. We will use a combination of Medical Subject Heading and free-text terms with various synonyms to search based on the Eligibility criteria. Two investigators independently reviewed the included studies and extracted relevant data. The relative risk (RR) and 95% confidence intervals (CIs) of were used as effect estimate. I-square (I(2)) test, substantial heterogeneity, sensitivity analysis and publication bias assessment will be performed accordingly. Stata 14.0 and Review Manger 5.3 are used for meta-analysis and systematic review. RESULTS: The results will be published in a peer-reviewed journal. CONCLUSION: The results of this review will be widely disseminated through peer-reviewed publications and conference presentations. This evidence may also provide helpful evidence of whether Tanreqing Injection therapy was efficient and safe in patients with viral pneumonia. PROSPERO REGISTRATION NUMBER: CRD42020164164.
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spelling pubmed-74896812020-09-24 Effects and safety of Tanreqing injection on viral pneumonia: A protocol for systematic review and meta-analysis Qiu, Yue Pan, Xue Su, Lin Lui, Hui Li, Ya-Dong Medicine (Baltimore) 6700 BACKGROUND: Influenza-related viral pneumonia is a severe threat to human health, which has caused high morbidity and mortality each year. The objective of this study was to assess the efficacy and safety of Tanreqing Injection therapy in patients with viral pneumonia. MATERIALS AND METHODS: This protocol established in this study has been reported following the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols. Web of Science, PubMed, EMBASE and the Cochrane Library were searched for clinical randomized trials in cases with viral pneumonia until 1st of July 2020. We will use a combination of Medical Subject Heading and free-text terms with various synonyms to search based on the Eligibility criteria. Two investigators independently reviewed the included studies and extracted relevant data. The relative risk (RR) and 95% confidence intervals (CIs) of were used as effect estimate. I-square (I(2)) test, substantial heterogeneity, sensitivity analysis and publication bias assessment will be performed accordingly. Stata 14.0 and Review Manger 5.3 are used for meta-analysis and systematic review. RESULTS: The results will be published in a peer-reviewed journal. CONCLUSION: The results of this review will be widely disseminated through peer-reviewed publications and conference presentations. This evidence may also provide helpful evidence of whether Tanreqing Injection therapy was efficient and safe in patients with viral pneumonia. PROSPERO REGISTRATION NUMBER: CRD42020164164. Lippincott Williams & Wilkins 2020-09-11 /pmc/articles/PMC7489681/ /pubmed/32925736 http://dx.doi.org/10.1097/MD.0000000000022022 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 6700
Qiu, Yue
Pan, Xue
Su, Lin
Lui, Hui
Li, Ya-Dong
Effects and safety of Tanreqing injection on viral pneumonia: A protocol for systematic review and meta-analysis
title Effects and safety of Tanreqing injection on viral pneumonia: A protocol for systematic review and meta-analysis
title_full Effects and safety of Tanreqing injection on viral pneumonia: A protocol for systematic review and meta-analysis
title_fullStr Effects and safety of Tanreqing injection on viral pneumonia: A protocol for systematic review and meta-analysis
title_full_unstemmed Effects and safety of Tanreqing injection on viral pneumonia: A protocol for systematic review and meta-analysis
title_short Effects and safety of Tanreqing injection on viral pneumonia: A protocol for systematic review and meta-analysis
title_sort effects and safety of tanreqing injection on viral pneumonia: a protocol for systematic review and meta-analysis
topic 6700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489681/
https://www.ncbi.nlm.nih.gov/pubmed/32925736
http://dx.doi.org/10.1097/MD.0000000000022022
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