Cargando…

Effect of Intramyocardial Grafting Collagen Scaffold With Mesenchymal Stromal Cells in Patients With Chronic Ischemic Heart Disease: A Randomized Clinical Trial

IMPORTANCE: Cell therapy may be helpful for cardiac disease but has been fraught with poor cell retention and survival after transplantation. OBJECTIVE: To determine whether cell-laden hydrogel treatment is safe and feasible for patients with chronic ischemic heart disease (CIHD). DESIGN, SETTING, A...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Xiaojun, Wang, Qiang, Zhao, Yannan, Zhang, He, Wang, Bin, Pan, Jun, Li, Jie, Yu, Hongming, Wang, Liudi, Dai, Jianwu, Wang, Dongjin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2020
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489863/ https://www.ncbi.nlm.nih.gov/pubmed/32910197 http://dx.doi.org/10.1001/jamanetworkopen.2020.16236

Ejemplares similares

Collagen scaffold enhances the regenerative properties of mesenchymal stromal cells
por: Rashedi, Iran, et al.
Publicado: (2017)

Effects of the intramyocardial implantation of stromal vascular fraction in patients with chronic ischemic cardiomyopathy
por: Comella, K., et al.
Publicado: (2016)

Intramyocardial Transplantation of Umbilical Cord Mesenchymal Stromal Cells in Chronic Ischemic Cardiomyopathy: A Controlled, Randomized Clinical Trial (HUC-HEART Trial)
por: Ulus, A. Tulga, et al.
Publicado: (2020)

A collagen-binding EGFR antibody fragment targeting tumors with a collagen-rich extracellular matrix
por: Liang, Hui, et al.
Publicado: (2016)

In Vivo MRI Tracking of Mesenchymal Stromal Cells Labeled with Ultrasmall Paramagnetic Iron Oxide Particles after Intramyocardial Transplantation in Patients with Chronic Ischemic Heart Disease
por: Mathiasen, Anders Bruun, et al.
Publicado: (2019)

Umbilical cord-derived mesenchymal stem cells on scaffolds facilitate collagen degradation via upregulation of MMP-9 in rat uterine scars
por: Xu, Lu, et al.
Publicado: (2017)

Biomimetic scaffold‐based stem cell transplantation promotes lung regeneration
por: Wang, Linjie, et al.
Publicado: (2023)

Accelerated Postero-Lateral Spinal Fusion by Collagen Scaffolds Modified with Engineered Collagen-Binding Human Bone Morphogenetic Protein-2 in Rats
por: Han, Xinglong, et al.
Publicado: (2014)

Human Cartilage Engineering in an In Vitro Repair Model Using Collagen Scaffolds and Mesenchymal Stromal Cells
por: Sanjurjo-Rodríguez, Clara, et al.
Publicado: (2017)

Collagen scaffold microenvironments modulate cell lineage commitment for differentiation of bone marrow cells into regulatory dendritic cells
por: Fang, Yongxiang, et al.
Publicado: (2017)

Three dimensional collagen scaffolds promote iPSC induction with higher pluripotency
por: Gu, Qi, et al.
Publicado: (2016)

Chitosan-collagen porous scaffold and bone marrow mesenchymal stem cell transplantation for ischemic stroke
por: Yan, Feng, et al.
Publicado: (2015)

Combining Injectable Plasma Scaffold with Mesenchymal Stem/Stromal Cells for Repairing Infarct Cavity after Ischemic Stroke
por: Zhang, Hongxia, et al.
Publicado: (2017)

Urethral Tissue Reconstruction Using the Acellular Dermal Matrix Patch Modified with Collagen-Binding VEGF in Beagle Urethral Injury Models
por: Wang, Yanni, et al.
Publicado: (2021)

The quality evaluation system establishment of mesenchymal stromal cells for cell-based therapy products
por: Xie, Yuanyuan, et al.
Publicado: (2020)

The effect of bone marrow mesenchymal stem cell and nano-hydroxyapatite/collagen I/poly-L-lactic acid scaffold implantation on the treatment of avascular necrosis of the femoral head in rabbits
por: Wang, Le, et al.
Publicado: (2019)

Aligned Scaffolds with Biomolecular Gradients for Regenerative Medicine
por: Li, Xiaoran, et al.
Publicado: (2019)

Mesenchymal stromal cell‐derived factors promote the colonization of collagen 3D scaffolds with human skin cells
por: Tutuianu, Raluca, et al.
Publicado: (2020)

Intramyocardial angiogenetic stem cells and epicardial erythropoietin save the acute ischemic heart
por: Klopsch, Christian, et al.
Publicado: (2018)

A Comparison of the Capacity of Mesenchymal Stromal Cells for Cartilage Regeneration Depending on Collagen-Based Injectable Biomimetic Scaffold Type
por: Sevastianov, Victor I., et al.
Publicado: (2021)

Collagen-grafted porous HDPE/PEAA scaffolds for bone reconstruction
por: Kim, Chang-Shik, et al.
Publicado: (2016)

Exosomes for Intramyocardial Intercellular Communication
por: Cervio, Elisabetta, et al.
Publicado: (2015)

Aging and the intramyocardial inflammatory response
por: Walley, Keith R
Publicado: (2014)

Collagen External Scaffolds Mitigate Intimal Hyperplasia and Improve Remodeling of Vein Grafts in a Rabbit Arteriovenous Graft Model
por: Li, Haiming, et al.
Publicado: (2017)

Transplantation of hUC-MSCs seeded collagen scaffolds reduces scar formation and promotes functional recovery in canines with chronic spinal cord injury
por: Li, Xing, et al.
Publicado: (2017)

An asymptomatic right atrial intramyocardial lipoma: a management dilemma
por: Wang, Haiyong, et al.
Publicado: (2015)

Mesenchymal Stromal Cells in Ischemic Brain Injury
por: Brooks, Beverly, et al.
Publicado: (2022)

Scaffold Chemical Model Based on Collagen—Methyl Methacrylate Graft Copolymers
por: Kuznetsova, Yulia L., et al.
Publicado: (2023)

Adult spinal cord tissue transplantation combined with local tacrolimus sustained‐release collagen hydrogel promotes complete spinal cord injury repair
por: Zhao, Xinhao, et al.
Publicado: (2023)

Osteoinduction and proliferation of bone-marrow stromal cells in three-dimensional poly (ε-caprolactone)/ hydroxyapatite/collagen scaffolds
por: Wang, Ting, et al.
Publicado: (2015)

Intramyocardial injection of hypoxia-conditioned extracellular vesicles modulates apoptotic signaling in chronically ischemic myocardium
por: Harris, Dwight D., et al.
Publicado: (2023)

Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells
por: Jia, Wei, et al.
Publicado: (2018)

Use of Natural Neural Scaffolds Consisting of Engineered Vascular Endothelial Growth Factor Immobilized on Ordered Collagen Fibers Filled in a Collagen Tube for Peripheral Nerve Regeneration in Rats
por: Ma, Fukai, et al.
Publicado: (2014)

Quantification of Intramyocardial Metabolites by Proton Magnetic Resonance Spectroscopy
por: Gillinder, Lisa, et al.
Publicado: (2015)

The Incorporation of Marine Coral Microparticles into Collagen-Based Scaffolds Promotes Osteogenesis of Human Mesenchymal Stromal Cells via Calcium Ion Signalling
por: Sheehy, Eamon J., et al.
Publicado: (2020)

Compression Bioreactor-Based Mechanical Loading Induces Mobilization of Human Bone Marrow-Derived Mesenchymal Stromal Cells into Collagen Scaffolds In Vitro
por: Gamez, Carolina, et al.
Publicado: (2020)

A gelatin/collagen/polycaprolactone scaffold for skin regeneration
por: Wei, Lin-Gwei, et al.
Publicado: (2019)

Renal cell carcinoma with intramyocardial metastases
por: Czarnecka, Anna M, et al.
Publicado: (2014)

Intramyocardial Hemorrhage: An Enigma for Cardiac MRI?
por: Calvieri, Camilla, et al.
Publicado: (2015)

An Unusual Case of Intramyocardial Dissecting Hematoma
por: Yuen, Ho-Chuen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kemh4jf20152mkifn0n60tsg2b