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Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes
Puromycin is an amino-acyl transfer RNA analog widely employed in studies of protein synthesis. Since puromycin is covalently incorporated into nascent polypeptide chains, anti-puromycin immunofluorescence enables visualization of nascent protein synthesis. A common assumption in studies of local me...
Autores principales: | Hobson, Benjamin D, Kong, Linghao, Hartwick, Erik W, Gonzalez, Ruben L, Sims, Peter A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490010/ https://www.ncbi.nlm.nih.gov/pubmed/32844746 http://dx.doi.org/10.7554/eLife.60048 |
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