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Down-Regulation of SREBP via PI3K/AKT/mTOR Pathway Inhibits the Proliferation and Invasion of Non-Small-Cell Lung Cancer Cells

BACKGROUND: Lung cancer is one of the most common causes of cancer-related deaths worldwide, metabolic disorders are also a problem that puzzles mankind. SREBP is overexpressed in non-small-cell lung cancer (NSCLC) and is also a key regulator of lipid synthesis. However, the mechanisms by which SREB...

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Detalles Bibliográficos
Autores principales:	Zhang, Bo, Wu, Jianchun, Guo, Peng, Wang, Yi, Fang, Zhihong, Tian, Jianhui, Yu, Yongchun, Teng, Wenjing, Luo, Yingbin, Li, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490059/ https://www.ncbi.nlm.nih.gov/pubmed/32982287 http://dx.doi.org/10.2147/OTT.S266073

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