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Choroidal Cavitary Disorders

The structure and functions of the choroid have been long acknowledged but the pathophysiology behind various anomalies has been difficult to understand until the advent of optical coherence tomography (OCT). With OCT imaging, choroidal cavitations appear as optically empty spaces between the outer...

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Detalles Bibliográficos
Autores principales: Nassar, Sandra, Tarbett, Aaron K, Browning, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490088/
https://www.ncbi.nlm.nih.gov/pubmed/32982154
http://dx.doi.org/10.2147/OPTH.S264731
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author Nassar, Sandra
Tarbett, Aaron K
Browning, David J
author_facet Nassar, Sandra
Tarbett, Aaron K
Browning, David J
author_sort Nassar, Sandra
collection PubMed
description The structure and functions of the choroid have been long acknowledged but the pathophysiology behind various anomalies has been difficult to understand until the advent of optical coherence tomography (OCT). With OCT imaging, choroidal cavitations appear as optically empty spaces between the outer retinal and choroidal layers with attenuation or loss of outer retinal layers. Choroidal cavitations are found in the posterior pole and seen in conditions such as pathologic myopia, north carolina macular dystrophy (NCMD), focal choroidal excavation (FCE), and torpedo maculopathy (TM). To date, these disorders have not been linked. A commonality they all share is malformation of the RPE-photoreceptor-choroid complex. The following report describes the differences and similarities of choroidal cavitation amongst the different retinal disorders and emphasizes the importance of multimodal imaging in the detection and management of potential complications.
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spelling pubmed-74900882020-09-24 Choroidal Cavitary Disorders Nassar, Sandra Tarbett, Aaron K Browning, David J Clin Ophthalmol Review The structure and functions of the choroid have been long acknowledged but the pathophysiology behind various anomalies has been difficult to understand until the advent of optical coherence tomography (OCT). With OCT imaging, choroidal cavitations appear as optically empty spaces between the outer retinal and choroidal layers with attenuation or loss of outer retinal layers. Choroidal cavitations are found in the posterior pole and seen in conditions such as pathologic myopia, north carolina macular dystrophy (NCMD), focal choroidal excavation (FCE), and torpedo maculopathy (TM). To date, these disorders have not been linked. A commonality they all share is malformation of the RPE-photoreceptor-choroid complex. The following report describes the differences and similarities of choroidal cavitation amongst the different retinal disorders and emphasizes the importance of multimodal imaging in the detection and management of potential complications. Dove 2020-09-08 /pmc/articles/PMC7490088/ /pubmed/32982154 http://dx.doi.org/10.2147/OPTH.S264731 Text en © 2020 Nassar et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Nassar, Sandra
Tarbett, Aaron K
Browning, David J
Choroidal Cavitary Disorders
title Choroidal Cavitary Disorders
title_full Choroidal Cavitary Disorders
title_fullStr Choroidal Cavitary Disorders
title_full_unstemmed Choroidal Cavitary Disorders
title_short Choroidal Cavitary Disorders
title_sort choroidal cavitary disorders
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490088/
https://www.ncbi.nlm.nih.gov/pubmed/32982154
http://dx.doi.org/10.2147/OPTH.S264731
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