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P53-regulated miR-320a targets PDL1 and is downregulated in malignant mesothelioma

Malignant pleural mesothelioma (MPM) is an aggressive cancer, related to asbestos exposure, which has a dismal prognosis. MPM diagnosis is late and often challenging, suggesting the need to identify more reliable molecular biomarkers. Here, we set out to identify differentially expressed miRNAs in e...

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Detalles Bibliográficos
Autores principales: Costa, Caterina, Indovina, Paola, Mattioli, Eliseo, Forte, Iris Maria, Iannuzzi, Carmelina Antonella, Luzzi, Luca, Bellan, Cristiana, De Summa, Simona, Bucci, Enrico, Di Marzo, Domenico, De Feo, Marisa, Mutti, Luciano, Pentimalli, Francesca, Giordano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490273/
https://www.ncbi.nlm.nih.gov/pubmed/32929059
http://dx.doi.org/10.1038/s41419-020-02940-w