Optimization and clinical validation of dual-target RT-LAMP for SARS-CoV-2

A novel reverse-transcriptase loop mediated amplification (RT-LAMP) method targeting genes encoding the Spike (S) protein and RNA-dependent RNA polymerase (RdRP) of SARS-CoV-2 has been developed. The LAMP assay achieves a comparable limit of detection (25–50 copies per reaction) to commonly used RT-...

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Detalles Bibliográficos
Autores principales: Mohon, Abu Naser, Oberding, Lisa, Hundt, Jana, van Marle, Guido, Pabbaraju, Kanti, Berenger, Byron M., Lisboa, Luiz, Griener, Thomas, Czub, Markus, Doolan, Cody, Servellita, Venice, Chiu, Charles Y., Greninger, Alexander L., Jerome, Keith R., Pillai, Dylan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490281/
https://www.ncbi.nlm.nih.gov/pubmed/32941977
http://dx.doi.org/10.1016/j.jviromet.2020.113972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490281/
https://www.ncbi.nlm.nih.gov/pubmed/32941977
http://dx.doi.org/10.1016/j.jviromet.2020.113972

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