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Optimization and clinical validation of dual-target RT-LAMP for SARS-CoV-2
A novel reverse-transcriptase loop mediated amplification (RT-LAMP) method targeting genes encoding the Spike (S) protein and RNA-dependent RNA polymerase (RdRP) of SARS-CoV-2 has been developed. The LAMP assay achieves a comparable limit of detection (25–50 copies per reaction) to commonly used RT-...
Autores principales: | Mohon, Abu Naser, Oberding, Lisa, Hundt, Jana, van Marle, Guido, Pabbaraju, Kanti, Berenger, Byron M., Lisboa, Luiz, Griener, Thomas, Czub, Markus, Doolan, Cody, Servellita, Venice, Chiu, Charles Y., Greninger, Alexander L., Jerome, Keith R., Pillai, Dylan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490281/ https://www.ncbi.nlm.nih.gov/pubmed/32941977 http://dx.doi.org/10.1016/j.jviromet.2020.113972 |
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