Multi-omic studies on missense PLG variants in families with otitis media

Otitis media (OM), a very common disease in young children, can result in hearing loss. In order to potentially replicate previously reported associations between OM and PLG, exome and Sanger sequencing, RNA-sequencing of saliva and middle ear samples, 16S rRNA sequencing, molecular modeling, and st...

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Detalles Bibliográficos
Autores principales: Bootpetch, Tori C., Hafrén, Lena, Elling, Christina L., Baschal, Erin E., Manichaikul, Ani W., Pine, Harold S., Szeremeta, Wasyl, Scholes, Melissa A., Cass, Stephen P., Larson, Eric D., Chan, Kenny H., Ishaq, Rafaqat, Prager, Jeremy D., Shaikh, Rehan S., Gubbels, Samuel P., Yousaf, Ayesha, Wine, Todd M., Bamshad, Michael J., Yoon, Patricia J., Jenkins, Herman A., Nickerson, Deborah A., Streubel, Sven-Olrik, Friedman, Norman R., Frank, Daniel N., Einarsdottir, Elisabet, Kere, Juha, Riazuddin, Saima, Daly, Kathleen A., Leal, Suzanne M., Ryan, Allen F., Mattila, Petri S., Ahmed, Zubair M., Sale, Michele M., Chonmaitree, Tasnee, Santos-Cortez, Regie Lyn P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490366/
https://www.ncbi.nlm.nih.gov/pubmed/32929111
http://dx.doi.org/10.1038/s41598-020-70498-w

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