Norepinephrine depleting toxin DSP-4 and LPS alter gut microbiota and induce neurotoxicity in α-synuclein mutant mice

This study examined the genetic mutation and toxicant exposure in producing gut microbiota alteration and neurotoxicity. Homozygous α-synuclein mutant (SNCA) mice that overexpress human A53T protein and littermate wild-type mice received a single injection of LPS (2 mg/kg) or a selective norepinephr...

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Detalles Bibliográficos
Autores principales: Song, Sheng, Liu, Jie, Zhang, Feng, Hong, Jau-Shyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490385/
https://www.ncbi.nlm.nih.gov/pubmed/32929122
http://dx.doi.org/10.1038/s41598-020-72202-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490385/
https://www.ncbi.nlm.nih.gov/pubmed/32929122
http://dx.doi.org/10.1038/s41598-020-72202-4

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