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A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation
NRF2 (NFE2L2) is a cytoprotective transcription factor associated with >60 human diseases, adverse drug reactions and therapeutic resistance. To provide insight into the complex regulation of NRF2 responses, 1962 predicted NRF2-partner interactions were systematically tested to generate an experi...
Autores principales: | Poh, Jonathan, Ponsford, Amy H., Boyd, James, Woodsmith, Jonathan, Stelzl, Ulrich, Wanker, Erich, Harper, Nicholas, MacEwan, David, Sanderson, Christopher M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490560/ https://www.ncbi.nlm.nih.gov/pubmed/32911434 http://dx.doi.org/10.1016/j.redox.2020.101686 |
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