Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche

The initiation of an intestinal tumour is a probabilistic process that depends on the competition between mutant and normal epithelial stem cells in crypts(1). Intestinal stem cells are closely associated with a diverse but poorly characterized network of mesenchymal cell types(2,3). However, whethe...

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Detalles Bibliográficos
Autores principales: Roulis, Manolis, Kaklamanos, Aimilios, Schernthanner, Marina, Bielecki, Piotr, Zhao, Jun, Kaffe, Eleanna, Frommelt, Laura-Sophie, Qu, Rihao, Knapp, Marlene S., Henriques, Ana, Chalkidi, Niki, Koliaraki, Vasiliki, Jiao, Jing, Brewer, J. Richard, Bacher, Maren, Blackburn, Holly N., Zhao, Xiaoyun, Breyer, Richard M., Aidinis, Vassilis, Jain, Dhanpat, Su, Bing, Herschman, Harvey R., Kluger, Yuval, Kollias, George, Flavell, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490650/
https://www.ncbi.nlm.nih.gov/pubmed/32322056
http://dx.doi.org/10.1038/s41586-020-2166-3

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