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Guillain-Barré syndrome presenting with COVID-19 infection
A construction worker in his 30s presented three times in 4 days with progressive upper and then lower limb weakness. On the first two occasions he had no systemic symptoms, but on the third presentation he had fever and cough, starting from day 4 of weakness. Examination identified weakness in all...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490909/ https://www.ncbi.nlm.nih.gov/pubmed/32928835 http://dx.doi.org/10.1136/bcr-2020-236978 |
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author | Ameer, Nasir Shekhda, Kalyan Mansukhbhai Cheesman, Ann |
author_facet | Ameer, Nasir Shekhda, Kalyan Mansukhbhai Cheesman, Ann |
author_sort | Ameer, Nasir |
collection | PubMed |
description | A construction worker in his 30s presented three times in 4 days with progressive upper and then lower limb weakness. On the first two occasions he had no systemic symptoms, but on the third presentation he had fever and cough, starting from day 4 of weakness. Examination identified weakness in all four limbs and areflexia, suggesting a peripheral neuromuscular disorder. Investigations were consistent with Guillain-Barré syndrome and additional COVID-19 (SARS-CoV-2) infection. The patient improved after immunoglobulin treatment. At least four cases of Guillain-Barré syndrome have been reported in the literature with concurrent COVID-19 illness in whom respiratory signs appeared a few days after the onset of neurological signs. With the incubation period for COVID-19 respiratory symptoms believed to be up to 14 days, it is possible that neurological symptoms could develop before respiratory and other symptoms. During the current pandemic, presence of concurrent COVID-19 infection needs to be considered in patients presenting with Guillain-Barré syndrome. |
format | Online Article Text |
id | pubmed-7490909 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-74909092020-09-15 Guillain-Barré syndrome presenting with COVID-19 infection Ameer, Nasir Shekhda, Kalyan Mansukhbhai Cheesman, Ann BMJ Case Rep New Disease A construction worker in his 30s presented three times in 4 days with progressive upper and then lower limb weakness. On the first two occasions he had no systemic symptoms, but on the third presentation he had fever and cough, starting from day 4 of weakness. Examination identified weakness in all four limbs and areflexia, suggesting a peripheral neuromuscular disorder. Investigations were consistent with Guillain-Barré syndrome and additional COVID-19 (SARS-CoV-2) infection. The patient improved after immunoglobulin treatment. At least four cases of Guillain-Barré syndrome have been reported in the literature with concurrent COVID-19 illness in whom respiratory signs appeared a few days after the onset of neurological signs. With the incubation period for COVID-19 respiratory symptoms believed to be up to 14 days, it is possible that neurological symptoms could develop before respiratory and other symptoms. During the current pandemic, presence of concurrent COVID-19 infection needs to be considered in patients presenting with Guillain-Barré syndrome. BMJ Publishing Group 2020-09-14 /pmc/articles/PMC7490909/ /pubmed/32928835 http://dx.doi.org/10.1136/bcr-2020-236978 Text en © BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | New Disease Ameer, Nasir Shekhda, Kalyan Mansukhbhai Cheesman, Ann Guillain-Barré syndrome presenting with COVID-19 infection |
title | Guillain-Barré syndrome presenting with COVID-19 infection |
title_full | Guillain-Barré syndrome presenting with COVID-19 infection |
title_fullStr | Guillain-Barré syndrome presenting with COVID-19 infection |
title_full_unstemmed | Guillain-Barré syndrome presenting with COVID-19 infection |
title_short | Guillain-Barré syndrome presenting with COVID-19 infection |
title_sort | guillain-barré syndrome presenting with covid-19 infection |
topic | New Disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490909/ https://www.ncbi.nlm.nih.gov/pubmed/32928835 http://dx.doi.org/10.1136/bcr-2020-236978 |
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