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Prolonged RNA shedding of the 2019 novel coronavirus in an asymptomatic patient with a VP shunt

A 33-year-old man with paranoid schizophrenia and a ventriculoperitoneal (VP) shunt was sent to our institution from an inpatient psychiatric facility due to concerns for the 2019 novel coronavirus (COVID-19). Per the facility, the patient had a fever and non-productive cough. On admission, the pati...

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Detalles Bibliográficos
Autores principales: El-Baba, Firas, Gabe, Danielle, Frank, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490917/
https://www.ncbi.nlm.nih.gov/pubmed/32928812
http://dx.doi.org/10.1136/bcr-2020-237720
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author El-Baba, Firas
Gabe, Danielle
Frank, Allan
author_facet El-Baba, Firas
Gabe, Danielle
Frank, Allan
author_sort El-Baba, Firas
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description A 33-year-old man with paranoid schizophrenia and a ventriculoperitoneal (VP) shunt was sent to our institution from an inpatient psychiatric facility due to concerns for the 2019 novel coronavirus (COVID-19). Per the facility, the patient had a fever and non-productive cough. On admission, the patient was afebrile and lacked subjective symptoms. A RNA reverse transcriptase PCR (RNA RT-PCR) test for COVID-19 was positive. A chest X-ray contained a small patchy opacity in the right middle lobe and another in the retrocardiac region concerning for pneumonia. Inflammatory markers were mildly elevated. He remained COVID-19 positive and asymptomatic for 36 days. This case details one asymptomatic carrier’s course with persistently positive COVID-19 nasopharyngeal swabs. It demonstrates that a VP shunt could be a possible predisposition for prolonged viral shedding.
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spelling pubmed-74909172020-09-25 Prolonged RNA shedding of the 2019 novel coronavirus in an asymptomatic patient with a VP shunt El-Baba, Firas Gabe, Danielle Frank, Allan BMJ Case Rep Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect A 33-year-old man with paranoid schizophrenia and a ventriculoperitoneal (VP) shunt was sent to our institution from an inpatient psychiatric facility due to concerns for the 2019 novel coronavirus (COVID-19). Per the facility, the patient had a fever and non-productive cough. On admission, the patient was afebrile and lacked subjective symptoms. A RNA reverse transcriptase PCR (RNA RT-PCR) test for COVID-19 was positive. A chest X-ray contained a small patchy opacity in the right middle lobe and another in the retrocardiac region concerning for pneumonia. Inflammatory markers were mildly elevated. He remained COVID-19 positive and asymptomatic for 36 days. This case details one asymptomatic carrier’s course with persistently positive COVID-19 nasopharyngeal swabs. It demonstrates that a VP shunt could be a possible predisposition for prolonged viral shedding. BMJ Publishing Group 2020-09-14 /pmc/articles/PMC7490917/ /pubmed/32928812 http://dx.doi.org/10.1136/bcr-2020-237720 Text en © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ. This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.https://bmj.com/coronavirus/usage
spellingShingle Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect
El-Baba, Firas
Gabe, Danielle
Frank, Allan
Prolonged RNA shedding of the 2019 novel coronavirus in an asymptomatic patient with a VP shunt
title Prolonged RNA shedding of the 2019 novel coronavirus in an asymptomatic patient with a VP shunt
title_full Prolonged RNA shedding of the 2019 novel coronavirus in an asymptomatic patient with a VP shunt
title_fullStr Prolonged RNA shedding of the 2019 novel coronavirus in an asymptomatic patient with a VP shunt
title_full_unstemmed Prolonged RNA shedding of the 2019 novel coronavirus in an asymptomatic patient with a VP shunt
title_short Prolonged RNA shedding of the 2019 novel coronavirus in an asymptomatic patient with a VP shunt
title_sort prolonged rna shedding of the 2019 novel coronavirus in an asymptomatic patient with a vp shunt
topic Findings That Shed New Light on the Possible Pathogenesis of a Disease or an Adverse Effect
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490917/
https://www.ncbi.nlm.nih.gov/pubmed/32928812
http://dx.doi.org/10.1136/bcr-2020-237720
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