Cargando…
Successful treatment of metastatic refractory gestational choriocarcinoma with pembrolizumab: A case for immune checkpoint salvage therapy in trophoblastic tumors
• Cure rates are high for choriocarcinoma, however chemoresistant disease often leads to death. • High expression of PD-L1 suggests a role for checkpoint inhibitors in choriocarcinoma. • Pembrolizumab should be considered for salvage therapy for chemoresistant choriocarcinoma.
Autores principales: | Clair, Kiran H., Gallegos, Nicolas, Bristow, Robert E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490982/ https://www.ncbi.nlm.nih.gov/pubmed/32964090 http://dx.doi.org/10.1016/j.gore.2020.100625 |
Ejemplares similares
-
Non-gestational choriocarcinoma with hyperprogression on pembrolizumab: A case report and review of the literature
por: Kazemi, Nazanin Yeganeh, et al.
Publicado: (2022) -
Hypersensitivity to Etoposide in Case of Metastatic Gestational Choriocarcinoma
por: Lazović, Biljana, et al.
Publicado: (2013) -
Combined chemotherapy and pembrolizumab salvages multi-chemotherapy agent and avelumab resistant choriocarcinoma: A case report
por: Lehmann, M., et al.
Publicado: (2023) -
An extrauterine extensively metastatic epithelioid trophoblastic tumor responsive to pembrolizumab
por: Bell, Sarah G., et al.
Publicado: (2021) -
Metastatic Choriocarcinoma of the Small Intestine Presenting as Refractory Anemia and Melena
por: Heil, Ross, et al.
Publicado: (2015)