Cargando…

Atrial Myopathy Underlying Atrial Fibrillation

While AF most often occurs in the setting of atrial disease, current assessment and treatment of patients with AF does not focus on the extent of the atrial myopathy that serves as the substrate for this arrhythmia. Atrial myopathy, in particular atrial fibrosis, may initiate a vicious cycle in whic...

Descripción completa

Detalles Bibliográficos
Autores principales: Rivner, Harold, Mitrani, Raul D, Goldberger, Jeffrey J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491052/
https://www.ncbi.nlm.nih.gov/pubmed/32983526
http://dx.doi.org/10.15420/aer.2020.13
_version_ 1783582141926342656
author Rivner, Harold
Mitrani, Raul D
Goldberger, Jeffrey J
author_facet Rivner, Harold
Mitrani, Raul D
Goldberger, Jeffrey J
author_sort Rivner, Harold
collection PubMed
description While AF most often occurs in the setting of atrial disease, current assessment and treatment of patients with AF does not focus on the extent of the atrial myopathy that serves as the substrate for this arrhythmia. Atrial myopathy, in particular atrial fibrosis, may initiate a vicious cycle in which atrial myopathy leads to AF, which in turn leads to a worsening myopathy. Various techniques, including ECG, plasma biomarkers, electroanatomical voltage mapping, echocardiography, and cardiac MRI, can help to identify and quantify aspects of the atrial myopathy. Current therapies, such as catheter ablation, do not directly address the underlying atrial myopathy. There is emerging research showing that by targeting this myopathy we can help decrease the occurrence and burden of AF.
format Online
Article
Text
id pubmed-7491052
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Radcliffe Cardiology
record_format MEDLINE/PubMed
spelling pubmed-74910522020-09-24 Atrial Myopathy Underlying Atrial Fibrillation Rivner, Harold Mitrani, Raul D Goldberger, Jeffrey J Arrhythm Electrophysiol Rev Clinical Arrhythmias While AF most often occurs in the setting of atrial disease, current assessment and treatment of patients with AF does not focus on the extent of the atrial myopathy that serves as the substrate for this arrhythmia. Atrial myopathy, in particular atrial fibrosis, may initiate a vicious cycle in which atrial myopathy leads to AF, which in turn leads to a worsening myopathy. Various techniques, including ECG, plasma biomarkers, electroanatomical voltage mapping, echocardiography, and cardiac MRI, can help to identify and quantify aspects of the atrial myopathy. Current therapies, such as catheter ablation, do not directly address the underlying atrial myopathy. There is emerging research showing that by targeting this myopathy we can help decrease the occurrence and burden of AF. Radcliffe Cardiology 2020-08 /pmc/articles/PMC7491052/ /pubmed/32983526 http://dx.doi.org/10.15420/aer.2020.13 Text en Copyright © 2020, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/legalcode This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.
spellingShingle Clinical Arrhythmias
Rivner, Harold
Mitrani, Raul D
Goldberger, Jeffrey J
Atrial Myopathy Underlying Atrial Fibrillation
title Atrial Myopathy Underlying Atrial Fibrillation
title_full Atrial Myopathy Underlying Atrial Fibrillation
title_fullStr Atrial Myopathy Underlying Atrial Fibrillation
title_full_unstemmed Atrial Myopathy Underlying Atrial Fibrillation
title_short Atrial Myopathy Underlying Atrial Fibrillation
title_sort atrial myopathy underlying atrial fibrillation
topic Clinical Arrhythmias
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491052/
https://www.ncbi.nlm.nih.gov/pubmed/32983526
http://dx.doi.org/10.15420/aer.2020.13
work_keys_str_mv AT rivnerharold atrialmyopathyunderlyingatrialfibrillation
AT mitranirauld atrialmyopathyunderlyingatrialfibrillation
AT goldbergerjeffreyj atrialmyopathyunderlyingatrialfibrillation