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Autonomous glucose metabolic reprogramming of tumour cells under hypoxia: opportunities for targeted therapy
Molecular oxygen (O(2)) is a universal electron acceptor that is eventually synthesized into ATP in the mitochondrial respiratory chain of all metazoans. Therefore, hypoxia biology has become an organizational principle of cell evolution, metabolism and pathology. Hypoxia-inducible factor (HIF) medi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491117/ https://www.ncbi.nlm.nih.gov/pubmed/32928258 http://dx.doi.org/10.1186/s13046-020-01698-5 |