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Autonomous glucose metabolic reprogramming of tumour cells under hypoxia: opportunities for targeted therapy

Molecular oxygen (O(2)) is a universal electron acceptor that is eventually synthesized into ATP in the mitochondrial respiratory chain of all metazoans. Therefore, hypoxia biology has become an organizational principle of cell evolution, metabolism and pathology. Hypoxia-inducible factor (HIF) medi...

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Detalles Bibliográficos
Autores principales: Huang, Mingyao, Yang, Liang, Peng, Xueqiang, Wei, Shibo, Fan, Qing, Yang, Shuo, Li, Xinyu, Li, Bowen, Jin, Hongyuan, Wu, Bo, Liu, Jingang, Li, Hangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491117/
https://www.ncbi.nlm.nih.gov/pubmed/32928258
http://dx.doi.org/10.1186/s13046-020-01698-5