Immunosenescence profile and expression of the aging biomarker (p16(INK4a)) in testicular cancer survivors treated with chemotherapy

BACKGROUND: Cytotoxic chemotherapy can cure advanced germ cell tumors. Nevertheless, cancer treatment may induce cellular senescence and accelerate molecular aging. The aging process implies an increase of cells expressing p16(INK4a) and changes in lymphocyte subpopulations. Our aim was to study the...

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Detalles Bibliográficos
Autores principales: Bourlon, Maria T., Velazquez, Hugo E., Hinojosa, Juan, Orozco, Luis, Rios-Corzo, Ricardo, Lima, Guadalupe, Llorente, Luis, Hernandez-Ramirez, Diego F., Valentin-Cortez, Francisco J., Medina-Rangel, Irene, Atisha-Fregoso, Yemil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491179/
https://www.ncbi.nlm.nih.gov/pubmed/32928147
http://dx.doi.org/10.1186/s12885-020-07383-2

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