Accurate determination of node and arc multiplicities in de bruijn graphs using conditional random fields

BACKGROUND: De Bruijn graphs are key data structures for the analysis of next-generation sequencing data. They efficiently represent the overlap between reads and hence, also the underlying genome sequence. However, sequencing errors and repeated subsequences render the identification of the true un...

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Detalles Bibliográficos
Autores principales: Steyaert, Aranka, Audenaert, Pieter, Fostier, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491180/
https://www.ncbi.nlm.nih.gov/pubmed/32928110
http://dx.doi.org/10.1186/s12859-020-03740-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491180/
https://www.ncbi.nlm.nih.gov/pubmed/32928110
http://dx.doi.org/10.1186/s12859-020-03740-x

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