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Accurate determination of node and arc multiplicities in de bruijn graphs using conditional random fields
BACKGROUND: De Bruijn graphs are key data structures for the analysis of next-generation sequencing data. They efficiently represent the overlap between reads and hence, also the underlying genome sequence. However, sequencing errors and repeated subsequences render the identification of the true un...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491180/ https://www.ncbi.nlm.nih.gov/pubmed/32928110 http://dx.doi.org/10.1186/s12859-020-03740-x |