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Neuroprotective activity of ursodeoxycholic acid in CHMP2B(Intron5) models of frontotemporal dementia

Frontotemporal dementia (FTD) is one of the most prevalent forms of early-onset dementia. It represents part of the FTD-Amyotrophic Lateral Sclerosis (ALS) spectrum, a continuum of genetically and pathologically overlapping disorders. FTD-causing mutations in CHMP2B, a gene encoding a core component...

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Detalles Bibliográficos
Autores principales:	West, Ryan J.H., Ugbode, Chris, Fort-Aznar, Laura, Sweeney, Sean T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491204/ https://www.ncbi.nlm.nih.gov/pubmed/32801000 http://dx.doi.org/10.1016/j.nbd.2020.105047

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